Details for OptiMAS: A decision support tool for marker-assisted assembly of diverse alleles

Valente F, Gauthier F, Bardol N, Blanc G, Joets J, Charcosset A, and Moreau L (2013). OptiMAS: A decision support tool for marker-assisted assembly of diverse alleles. Journal of Heredity published online April 10, 2013. (DOI: 10.1093/jhered/est020). (G8009.03.06.02/Subactivity 2.2.6.2).

Current advances in plant genotyping lead to major progress in the knowledge of genetic architecture of traits of interest. It is increasingly important to develop decision support tools to help breeders and geneticists to conduct marker-assisted selection methods to assemble favorable alleles that are discovered. Algorithms have been implemented, within an interactive graphical interface, to 1) trace parental alleles throughout generations, 2) propose strategies to select the best plants based on estimated molecular scores, and 3) efficiently intermate them depending on the expected value of their progenies. With the possibility to consider a multi-allelic context, OptiMAS opens new prospects to assemble favorable alleles issued from diverse parents and further accelerate genetic gain.

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